As your skin ages, repeated expressions cause lasting lines and wrinkles. Neuromodulators such as Xeomin®, Botox®, and Dysport® are non-invasive treatments that provide a natural, youthful appearance by reducing the appearance of fine lines and wrinkles. Xeomin®, Botox®, and Dysport® all share the same active ingredient: Botulinum type A, which acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, neuromodulators can temporarily reduce the appearance of fine lines and wrinkles. A small amount of neuromodulator is injected into the underlying muscle, which makes it relax and smooths the appearance of the overlying skin.
Xeomin®, Botox®, and Dysport® are all FDA and Health Canada approved neuromodulators that are used by clinicians across the world. They all minimize and block movement. Although the functionalities of each injectable do share certain consistencies, there are also some slight differences between Xeomin®, Botox®, and Dysport®
Xeomin® has been on the global market since 2002 with over 10 years of efficacy and safety in Canada. Xeomin® creates the same muscle paralysis to smooth the look of fine lines and wrinkles, however, it is the only neuromodulator that is free from unnecessary proteins. Xeomin®has no additives, as botulinum toxin is the only ingredient present. For that reason, Xeomin® is often referred to as “Naked Botox”. Due to the purity of Xeomin®, it is less susceptible to resistance and less likely to cause an allergic reaction. Results typically take about one week to appear, with full results in about two weeks.
Botox® is the most well-known and researched brand of neuromodulator, likely because it was the first neuromodulator available. Since FDA approval in 2002, Botox® is the #1 selling neuromodulator on the market. Botox® is FDA approved for the simultaneous treatment of moderate to severe forehead lines, lateral canthal lines, and glabellar lines. Like Xeomin®, its ingredients stay isolated and spreads less than Dysport®, so it can be more effective for specific treatment areas that require more attention. Botox uses ONA molecules that are great for the treatment of large muscles and deep folds. Results typically take about one week to appear, with full results in about two weeks.
Dysport® was approved by the FDA in 2009 and approved in Canada for cosmetic use in 2014. One unique difference of Dysport® compared to Botox® or Xeomin® is that the molecules are smaller, resulting in more spreading across the injection site. This diffusion extends a greater distance in the muscle, creating a softer, natural look. The ABO molecules in Dysport® may be more appropriate for larger surface areas and milder concerns. Results are typically seen in only 2-3 days, with full results in about two weeks.
Xeomin®, Botox®, and Dysport® are all effective treatment options for fine lines and wrinkles with slight differences such as their molecular weight (which affects the dispersion), the additives, and how quickly the results begin to take effect. Botox® and Xeomin® tend to be better suited for treating deeper fine lines and wrinkles with a more precise, targeted approach. Dysport® has a faster onset than Xeomin® and Botox®. Botox® and Dysport® have complex proteins that surround the toxin, whereas Xeomin® has no additional proteins. The purity of Xeomin® reduces the risk of resistance and allergic reaction. Botox® has been around the longest and is the most studied neuromodulator. All three options produce results that peak at two weeks and last around 3-4 months, depending on the individual. Options need to be considered on a case-by-case basis with a thorough consultation with the Nurse Practitioner.
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~ 15-15 units
~ 15-30 units
~6-30 units
~40-100 units
~6-14 units
Prior to neuromodulator treatment
*Prices subject to change
Rewind and Renew Medical Aesthetics
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